• Users Online: 1009
  • Print this page
  • Email this page
RESEARCH ARTICLE
Year : 2014  |  Volume : 3  |  Issue : 3  |  Page : 3

Can plasma fibrinogen levels predict bleeding after coronary artery bypass grafting?


1 Department of Cardiac Anesthesiology, Baqiyatallah University of Medical Sciences, Tehran, IR Iran
2 Department of Anesthesiology, Baqiyatallah University of Medical Sciences, Tehran, IR Iran
3 Center for Nursing Care Research, Shahid Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran
4 Mental Health Research Center, Iran University of Medical Sciences, Tehran, IR Iran
5 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Correspondence Address:
Mohammadsaeid Ghiasi
Department of Cardiac Anesthesiology, Baqiyatallah University of Medical Sciences, Tehran
IR Iran
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.5812/cardiovascmed.19521

Get Permissions

Background: Fibrinogen is the main biomarker for bleeding. To prevent excessive postoperative bleeding, it would be useful to identify high-risk patients before coronary artery bypass grafting (CABG). Objectives: In order to predicating bleeding after CABG, we sought to determine whether preoperative fibrinogen concentration was associated with the amount of bleeding following CABG. Patients and Methods: A total of 144 patients (mean age = 61.50 ± 9.42 years; 65.7% men), undergoing elective and isolated CABG, were included in this case-series study. The same anesthesia technique and medicines were selected for all the patients. In the ICU, the patients were assessed in terms of bleeding at 12 and 24 hours post-operation, amount of contingent blood products received, and relevant tests. Statistical tests were subsequently conducted to analyze the correlation between preoperative fibrinogen concentration and the amount of post-CABG bleeding. Results: The mean and standard deviation of bleeding at 12 and 24 hours post-operation was 285.37 ± 280.27 and 499.31 ± 355.57 mL, respectively. The results showed that postoperative bleeding was associated with different factors whereas pre-anesthesia fibrinogen was not correlated with bleeding at 12 (P = 0.856) and 24 hours (P = 0.936) post-operation. There were correlations between the extra-corporal circulation time and bleeding at 12 hours post-operation (ρ = 0.231, P = 0.007) and bleeding at 24 hours post-operation (ρ = 0.218, P = 0.013). Conclusions: Preoperative assessment of plasma fibrinogen levels failed to predict post-CABG bleeding.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed509    
    Printed12    
    Emailed0    
    PDF Downloaded60    
    Comments [Add]    
    Cited by others 1    

Recommend this journal